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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA-templated DNA replication
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Accession:GO:0006261 term browser browse the term
Definition:A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.
Synonyms:exact_synonym: DNA-dependent DNA replication
 alt_id: GO:0006262;   GO:0006263

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DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAZ1A bromodomain adjacent to zinc finger domain 1A involved_in ISO (PMID:12434153) UniProt PMID:12434153 NCBI chr24:11,580,379...11,708,320
Ensembl chr24:11,581,164...11,706,292 		JBrowse link
G CHRAC1 chromatin accessibility complex subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:134,745,776...134,751,830
Ensembl chr 8:134,746,549...134,752,018 		JBrowse link
G GINS2 GINS complex subunit 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr 5:71,088,766...71,099,845
Ensembl chr 5:71,089,564...71,099,688 		JBrowse link
G GINS4 GINS complex subunit 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:39,509,833...39,523,099
Ensembl chr 8:39,509,847...39,526,321 		JBrowse link
G HELB DNA helicase B acts_upstream_of_or_within ISO (PMID:11557815) MGI PMID:11557815 NCBI chr11:61,972,061...62,008,532
Ensembl chr11:61,972,161...62,012,631 		JBrowse link
G LOC103235079 transcription factor Spi-B involved_in IEA UniProt
TreeGrafter		 GO_REF:0000117 GO_REF:0000118 NCBI chr 6:43,446,466...43,490,377
Ensembl chr 6:43,460,747...43,480,112
Ensembl chr 6:43,460,747...43,480,112 		JBrowse link
G MCMBP minichromosome maintenance complex binding protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:112,622,094...112,665,573
Ensembl chr 9:112,621,784...112,665,589 		JBrowse link
G NYNRIN NYN domain and retroviral integrase containing involved_in IEA UniProt GO_REF:0000117 NCBI chr24:1,380,864...1,401,710
Ensembl chr24:1,381,483...1,401,750 		JBrowse link
G ORC6 origin recognition complex subunit 6 acts_upstream_of_or_within ISO (PMID:20219456) MGI PMID:20219456 NCBI chr 5:32,538,451...32,547,667
Ensembl chr 5:32,539,847...32,547,778 		JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit involved_in IEA UniProt GO_REF:0000117 NCBI chr  X:23,184,921...23,492,836
Ensembl chr  X:23,185,046...23,492,992 		JBrowse link
G POLD2 DNA polymerase delta 2, accessory subunit involved_in ISO
IEA		 RGD
Ensembl		 PMID:7503737 GO_REF:0000107 RGD:2307013 NCBI chr21:14,544,083...14,553,315
Ensembl chr21:14,545,986...14,553,217 		JBrowse link
G POLD3 DNA polymerase delta 3, accessory subunit involved_in ISO (PMID:20334433) RGD
ComplexPortal		 PMID:7503737 PMID:20334433 RGD:2307013 NCBI chr 1:65,832,887...65,885,671 JBrowse link
G POLD4 DNA polymerase delta 4, accessory subunit involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:7503737 GO_REF:0000118 RGD:2307013 NCBI chr 1:6,910,044...6,912,134
Ensembl chr 1:6,910,159...6,911,813 		JBrowse link
G POLE DNA polymerase epsilon, catalytic subunit involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr11:127,966,879...128,030,442
Ensembl chr11:127,965,896...128,030,292 		JBrowse link
G POLE2 DNA polymerase epsilon 2, accessory subunit involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr24:26,682,627...26,736,266
Ensembl chr24:26,682,723...26,736,171 		JBrowse link
G POLE3 DNA polymerase epsilon 3, accessory subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,162,934...26,164,931
Ensembl chr12:26,163,107...26,165,214 		JBrowse link
G POLE4 DNA polymerase epsilon 4, accessory subunit involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:32,313,399...32,320,084
Ensembl chr14:32,312,893...32,320,016 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit involved_in IEA UniProt GO_REF:0000117 NCBI chr29:7,864,319...7,881,577
Ensembl chr29:7,863,277...7,882,068 		JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:56,773,867...56,794,571
Ensembl chr16:56,776,330...56,794,654 		JBrowse link
G POLN DNA polymerase nu involved_in IEA InterPro GO_REF:0000002 Ensembl chr27:46,568,587...46,690,968 JBrowse link
G POLQ DNA polymerase theta involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chr22:59,336,506...59,448,609
Ensembl chr22:59,336,842...59,448,604 		JBrowse link
G PRIM2 DNA primase subunit 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr17:13,995,488...14,304,161
Ensembl chr17:13,995,401...14,304,156 		JBrowse link
G REV3L REV3 like, DNA directed polymerase zeta catalytic subunit involved_in IEA UniProt GO_REF:0000117 NCBI chr13:62,400,241...62,586,645
Ensembl chr13:62,399,745...62,586,647 		JBrowse link
G RFC1 replication factor C subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:10,936,445...11,013,457
Ensembl chr27:10,936,461...11,006,679 		JBrowse link
G RFC2 replication factor C subunit 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr28:8,818,606...8,846,929
Ensembl chr28:8,818,650...8,847,865 		JBrowse link
G RFC3 replication factor C subunit 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:12,525,512...12,545,046
Ensembl chr 3:12,525,544...12,545,134 		JBrowse link
G RFC4 replication factor C subunit 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:81,081,415...81,097,599
Ensembl chr15:81,081,481...81,097,272 		JBrowse link
G RFC5 replication factor C subunit 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:113,352,342...113,368,147
Ensembl chr11:113,352,378...113,370,829 		JBrowse link
G WDHD1 WD repeat and HMG-box DNA binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:32,118,688...32,204,464
Ensembl chr24:32,117,375...32,204,388 		JBrowse link
G WDR18 WD repeat domain 18 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:740,712...750,797
Ensembl chr 6:740,729...754,592 		JBrowse link
G WRNIP1 WRN helicase interacting protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:69,366,565...69,386,950
Ensembl chr17:69,366,389...69,386,932 		JBrowse link
DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZPR1 ZPR1 zinc finger involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,144,247...108,153,533
Ensembl chr 1:108,144,609...108,153,480 		JBrowse link
DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNE1 cyclin E1 acts_upstream_of_or_within ISO (PMID:12941272) MGI PMID:12941272 NCBI chr 6:24,879,923...24,888,985 JBrowse link
G CCNE1 cyclin E1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:24,880,536...24,888,435 JBrowse link
G CCNE2 cyclin E2 acts_upstream_of_or_within ISO (PMID:12941272) MGI PMID:12941272 NCBI chr 8:89,846,670...89,863,432
Ensembl chr 8:89,848,077...89,862,037 		JBrowse link
G CDC45 cell division cycle 45 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr19:6,232,610...6,275,743
Ensembl chr19:6,231,591...6,275,294 		JBrowse link
G CDC6 cell division cycle 6 involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr16:65,873,341...65,888,180
Ensembl chr16:65,871,627...65,888,217 		JBrowse link
G MCM10 minichromosome maintenance 10 replication initiation factor involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:13,200,018...13,252,830
Ensembl chr 9:13,204,246...13,253,367 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr22:53,419,958...53,452,720
Ensembl chr22:53,420,417...53,444,095 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:20,222,440...20,243,807
Ensembl chr17:20,222,590...20,243,809 		JBrowse link
G MCM4 minichromosome maintenance complex component 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:44,120,291...44,136,625
Ensembl chr 8:44,120,301...44,138,193 		JBrowse link
G MCM5 minichromosome maintenance complex component 5 involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr19:18,164,743...18,189,223
Ensembl chr19:18,164,879...18,189,284 		JBrowse link
G MCM6 minichromosome maintenance complex component 6 involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr10:20,053,726...20,089,571
Ensembl chr10:20,051,138...20,089,545 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr28:12,976,487...12,985,354
Ensembl chr28:12,977,013...12,985,898 		JBrowse link
G NOC3L NOC3 like DNA replication regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:87,563,766...87,593,534
Ensembl chr 9:87,564,693...87,593,512 		JBrowse link
G ORC1 origin recognition complex subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:80,540,331...80,571,989
Ensembl chr20:80,542,532...80,572,237 		JBrowse link
G ORC2 origin recognition complex subunit 2 involved_in ISO (PMID:16549788) ComplexPortal PMID:16549788 NCBI chr10:86,567,350...86,629,693
Ensembl chr10:86,564,332...86,629,855 		JBrowse link
G ORC3 origin recognition complex subunit 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:12,068,167...12,159,079
Ensembl chr13:12,068,235...12,159,401 		JBrowse link
G ORC4 origin recognition complex subunit 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:33,314,020...33,401,770
Ensembl chr10:33,314,271...33,355,588 		JBrowse link
G ORC5 origin recognition complex subunit 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:73,082,527...73,148,683
Ensembl chr21:73,083,032...73,148,647 		JBrowse link
G ORC6 origin recognition complex subunit 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:32,538,451...32,547,667
Ensembl chr 5:32,539,847...32,547,778 		JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit involved_in ISO (PMID:2175912), (PMID:26975377)
(MGI:3687659|PMID:10523676)		 ComplexPortal PMID:2175912 PMID:10523676 PMID:26975377 MGI:3687659 NCBI chr  X:23,184,921...23,492,836
Ensembl chr  X:23,185,046...23,492,992 		JBrowse link
G POLA2 DNA polymerase alpha 2, accessory subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:8,940,102...8,977,049
Ensembl chr 1:8,938,769...8,976,771 		JBrowse link
G PRIM1 DNA primase subunit 1 involved_in ISO (PMID:26975377)
(MGI:3687659|PMID:10523676)		 ComplexPortal PMID:10523676 PMID:26975377 MGI:3687659 NCBI chr11:52,676,890...52,699,337
Ensembl chr11:52,674,602...52,699,294 		JBrowse link
G PRIM2 DNA primase subunit 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:13,995,488...14,304,161
Ensembl chr17:13,995,401...14,304,156 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:56,679,333...56,740,773
Ensembl chr15:56,679,426...56,741,566 		JBrowse link
DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 5:74,190,409...74,196,589
Ensembl chr 5:74,190,947...74,195,972 		JBrowse link
G GMNN geminin DNA replication inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:47,462,647...47,474,445
Ensembl chr17:47,461,645...47,474,417 		JBrowse link
DNA replication proofreading term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103235079 transcription factor Spi-B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:43,446,466...43,490,377
Ensembl chr 6:43,460,747...43,480,112
Ensembl chr 6:43,460,747...43,480,112 		JBrowse link
G POLE DNA polymerase epsilon, catalytic subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:127,966,879...128,030,442
Ensembl chr11:127,965,896...128,030,292 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit involved_in ISO (PMID:37202477)
(PMID:11897778)		 UniProt PMID:11897778 PMID:37202477 NCBI chr29:7,864,319...7,881,577
Ensembl chr29:7,863,277...7,882,068 		JBrowse link
DNA replication, Okazaki fragment processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNA2 DNA replication helicase/nuclease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:62,926,221...62,985,843
Ensembl chr 9:62,926,674...62,985,842 		JBrowse link
DNA replication, synthesis of primer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HELB DNA helicase B involved_in ISO (PMID:12181327) UniProt PMID:12181327 NCBI chr11:61,972,061...62,008,532
Ensembl chr11:61,972,161...62,012,631 		JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit involved_in ISO (MGI:6478526|PMID:8026492)
(PMID:2175912), (PMID:27019227), (PMID:8026492)		 UniProt PMID:2175912 PMID:8026492 PMID:27019227 MGI:6478526 NCBI chr  X:23,184,921...23,492,836
Ensembl chr  X:23,185,046...23,492,992 		JBrowse link
G POLA2 DNA polymerase alpha 2, accessory subunit involved_in ISO (MGI:6478526|PMID:8026492)
(PMID:8026492)		 UniProt PMID:8026492 MGI:6478526 NCBI chr 1:8,940,102...8,977,049
Ensembl chr 1:8,938,769...8,976,771 		JBrowse link
G POLRMT RNA polymerase mitochondrial involved_in IEA GOC GO_REF:0000108 NCBI chr 6:358,865...377,007
Ensembl chr 6:358,917...377,089 		JBrowse link
G PRIM1 DNA primase subunit 1 involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr11:52,676,890...52,699,337
Ensembl chr11:52,674,602...52,699,294 		JBrowse link
G PRIM2 DNA primase subunit 2 involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr17:13,995,488...14,304,161
Ensembl chr17:13,995,401...14,304,156 		JBrowse link
G PRIMPOL primase and DNA directed polymerase involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:130,611,105...130,653,614
Ensembl chr 7:130,611,133...130,657,450 		JBrowse link
DNA strand elongation involved in DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCM3 minichromosome maintenance complex component 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:20,222,440...20,243,807
Ensembl chr17:20,222,590...20,243,809 		JBrowse link
G MCM4 minichromosome maintenance complex component 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:44,120,291...44,136,625
Ensembl chr 8:44,120,301...44,138,193 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr28:12,976,487...12,985,354
Ensembl chr28:12,977,013...12,985,898 		JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit involved_in ISO (PMID:4084590) UniProt PMID:4084590 NCBI chr  X:23,184,921...23,492,836
Ensembl chr  X:23,185,046...23,492,992 		JBrowse link
G POLD2 DNA polymerase delta 2, accessory subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:14,544,083...14,553,315
Ensembl chr21:14,545,986...14,553,217 		JBrowse link
G POLD3 DNA polymerase delta 3, accessory subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:65,832,887...65,885,671 JBrowse link
DNA strand elongation involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103216161 uncharacterized LOC103216161 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:56,448,443...56,467,908
Ensembl chr 2:56,448,392...56,467,712 		JBrowse link
DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXO1 exonuclease 1 involved_in ISO (PMID:26240375) UniProt PMID:26240375 NCBI chr25:78,934,337...78,976,346
Ensembl chr25:78,934,459...78,976,219 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease involved_in ISO (MGI:3839734|PMID:18854157)
(PMID:27814491), (PMID:27889449), (PMID:29670289), (PMID:30464262), (PMID:30612738), (PMID:30787182), (PMID:37696958)		 UniProt PMID:18854157 PMID:27814491 PMID:27889449 PMID:29670289 PMID:30464262 More... MGI:3839734 NCBI chr 1:85,615,448...85,694,247
Ensembl chr 1:85,610,819...85,694,269 		JBrowse link
G NBN nibrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:85,017,807...85,069,219
Ensembl chr 8:85,015,752...85,069,028 		JBrowse link
G RAD50 RAD50 double strand break repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:35,375,206...35,458,801
Ensembl chr23:35,375,305...35,458,622 		JBrowse link
G RBBP8 RB binding protein 8, endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:57,501,070...57,617,301
Ensembl chr18:57,501,271...57,597,670 		JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:57,641,634...57,699,685
Ensembl chr 2:57,639,046...57,699,525 		JBrowse link
DNA synthesis involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TK1 thymidine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:70,186,103...70,200,689
Ensembl chr16:70,186,767...70,200,610 		JBrowse link
DNA unwinding involved in DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr29:9,046,485...9,152,320
Ensembl chr29:9,045,373...9,152,254 		JBrowse link
G CDC45 cell division cycle 45 involved_in ISO (PMID:22474384) ComplexPortal PMID:22474384 NCBI chr19:6,232,610...6,275,743
Ensembl chr19:6,231,591...6,275,294 		JBrowse link
G GINS2 GINS complex subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,088,766...71,099,845
Ensembl chr 5:71,089,564...71,099,688 		JBrowse link
G GINS3 GINS complex subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,331,392...44,342,754
Ensembl chr 5:44,331,802...44,342,812 		JBrowse link
G GINS4 GINS complex subunit 4 involved_in ISO (PMID:22474384) ComplexPortal PMID:22474384 NCBI chr 8:39,509,833...39,523,099
Ensembl chr 8:39,509,847...39,526,321 		JBrowse link
G LOC103216161 uncharacterized LOC103216161 involved_in ISO (PMID:22474384) ComplexPortal PMID:22474384 NCBI chr 2:56,448,443...56,467,908
Ensembl chr 2:56,448,392...56,467,712 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10531422) Ensembl
MGI
TreeGrafter		 PMID:10531422 GO_REF:0000107 GO_REF:0000118 NCBI chr22:53,419,958...53,452,720
Ensembl chr22:53,420,417...53,444,095 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:20,222,440...20,243,807
Ensembl chr17:20,222,590...20,243,809 		JBrowse link
G MCM4 minichromosome maintenance complex component 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15917436) Ensembl
MGI
TreeGrafter		 PMID:15917436 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:44,120,291...44,136,625
Ensembl chr 8:44,120,301...44,138,193 		JBrowse link
G MCM5 minichromosome maintenance complex component 5 involved_in ISO (PMID:22474384) ComplexPortal PMID:22474384 NCBI chr19:18,164,743...18,189,223
Ensembl chr19:18,164,879...18,189,284 		JBrowse link
G MCM6 minichromosome maintenance complex component 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15917436) Ensembl
MGI
TreeGrafter		 PMID:15917436 GO_REF:0000107 GO_REF:0000118 NCBI chr10:20,053,726...20,089,571
Ensembl chr10:20,051,138...20,089,545 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15917436) TreeGrafter
MGI		 PMID:15917436 GO_REF:0000118 NCBI chr28:12,976,487...12,985,354
Ensembl chr28:12,977,013...12,985,898 		JBrowse link
G PURA purine rich element binding protein A involved_in ISO (PMID:15777841) UniProt PMID:15777841 NCBI chr23:42,757,963...42,767,393
Ensembl chr23:42,764,263...42,765,231 		JBrowse link
G RAD51 RAD51 recombinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:42,281,085...42,319,394
Ensembl chr26:42,279,608...42,318,169 		JBrowse link
G RECQL RecQ like helicase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:21,334,601...21,366,943
Ensembl chr11:21,331,584...21,366,979 		JBrowse link
G RECQL4 RecQ like helicase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:138,725,494...138,732,286
Ensembl chr 8:138,725,633...138,732,096 		JBrowse link
G RECQL5 RecQ like helicase 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:46,013,100...46,052,713
Ensembl chr16:46,013,092...46,056,167 		JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:110,492,340...110,504,176
Ensembl chr21:110,492,377...110,504,177 		JBrowse link
G TWNK twinkle mtDNA helicase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11431692) Ensembl
MGI		 PMID:11431692 GO_REF:0000107 NCBI chr 9:94,006,183...94,012,783
Ensembl chr 9:94,006,188...94,013,164 		JBrowse link
G WRN WRN RecQ like helicase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:29,150,256...29,288,830
Ensembl chr 8:29,174,229...29,289,129 		JBrowse link
lagging strand elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIG1 DNA ligase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:41,354,701...41,405,417
Ensembl chr 6:41,351,389...41,403,421 		JBrowse link
G LIG3 DNA ligase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:28,487,953...28,511,945
Ensembl chr16:28,490,434...28,511,130 		JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:23,184,921...23,492,836
Ensembl chr  X:23,185,046...23,492,992 		JBrowse link
leading strand elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCNA proliferating cell nuclear antigen involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991 		JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:23,184,921...23,492,836
Ensembl chr  X:23,185,046...23,492,992 		JBrowse link
G POLE DNA polymerase epsilon, catalytic subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:127,966,879...128,030,442
Ensembl chr11:127,965,896...128,030,292 		JBrowse link
G POLE3 DNA polymerase epsilon 3, accessory subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:26,162,934...26,164,931
Ensembl chr12:26,163,107...26,165,214 		JBrowse link
mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCM9 minichromosome maintenance 9 homologous recombination repair factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:54,945,668...55,069,869
Ensembl chr13:54,945,786...55,070,328 		JBrowse link
mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNA2 DNA replication helicase/nuclease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:62,926,221...62,985,843
Ensembl chr 9:62,926,674...62,985,842 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 acts_upstream_of_or_within ISO (PMID:16327803) MGI PMID:16327803 NCBI chr 5:4,109,612...4,139,789 JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:4,109,577...4,137,926 JBrowse link
G MGME1 mitochondrial genome maintenance exonuclease 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:47,028,568...47,050,950
Ensembl chr 2:47,029,329...47,050,948 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15888483) InterPro
MGI
TreeGrafter		 PMID:15888483 GO_REF:0000002 GO_REF:0000118 NCBI chr29:7,864,319...7,881,577
Ensembl chr29:7,863,277...7,882,068 		JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23197651) Ensembl
MGI
TreeGrafter		 PMID:23197651 GO_REF:0000107 GO_REF:0000118 NCBI chr16:56,773,867...56,794,571
Ensembl chr16:56,776,330...56,794,654 		JBrowse link
G PRIMPOL primase and DNA directed polymerase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:130,611,105...130,653,614
Ensembl chr 7:130,611,133...130,657,450 		JBrowse link
G RNASEH1 ribonuclease H1 acts_upstream_of_or_within ISO (PMID:12667461) MGI PMID:12667461 NCBI chr14:104,095,771...104,111,051
Ensembl chr14:104,095,795...104,114,987 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:62,606,112...62,649,979
Ensembl chr 1:62,604,486...62,650,200 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in
acts_upstream_of_or_within		 ISO (PMID:17486094) ComplexPortal
MGI		 PMID:17486094 NCBI chr 8:97,055,111...97,091,980 JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 8:97,055,012...97,092,182 JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:110,492,340...110,504,176
Ensembl chr21:110,492,377...110,504,177 		JBrowse link
G TEFM transcription elongation factor, mitochondrial NOT|involved_in ISO (PMID:21278163) UniProt PMID:21278163 NCBI chr16:25,601,744...25,609,071
Ensembl chr16:25,601,941...25,608,209 		JBrowse link
G TK2 thymidine kinase 2 acts_upstream_of_or_within ISO (PMID:18434326) MGI PMID:18434326 NCBI chr 5:52,202,040...52,272,428
Ensembl chr 5:52,204,605...52,243,017 		JBrowse link
G TWNK twinkle mtDNA helicase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:94,006,183...94,012,783
Ensembl chr 9:94,006,188...94,013,164 		JBrowse link
mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCM6 minichromosome maintenance complex component 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:20,053,726...20,089,571
Ensembl chr10:20,051,138...20,089,545 		JBrowse link
mitotic DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GINS3 GINS complex subunit 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:44,331,392...44,342,754
Ensembl chr 5:44,331,802...44,342,812 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:53,419,958...53,452,720
Ensembl chr22:53,420,417...53,444,095 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:20,222,440...20,243,807
Ensembl chr17:20,222,590...20,243,809 		JBrowse link
G MCM4 minichromosome maintenance complex component 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:44,120,291...44,136,625
Ensembl chr 8:44,120,301...44,138,193 		JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr  X:23,184,921...23,492,836
Ensembl chr  X:23,185,046...23,492,992 		JBrowse link
mitotic DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC45 cell division cycle 45 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:6,232,610...6,275,743
Ensembl chr19:6,231,591...6,275,294 		JBrowse link
mitotic DNA replication termination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RTF2 replication termination factor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:7,601,916...7,653,374
Ensembl chr 2:7,602,531...7,653,328 		JBrowse link
mitotic DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RECQL5 RecQ like helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,013,100...46,052,713
Ensembl chr16:46,013,092...46,056,167 		JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated involved_in ISO (PMID:21076401) BHF-UCL PMID:21076401 NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213 		JBrowse link
G RAD51 RAD51 recombinase involved_in IEA InterPro GO_REF:0000002 NCBI chr26:42,281,085...42,319,394
Ensembl chr26:42,279,608...42,318,169 		JBrowse link
mitotic telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNA2 DNA replication helicase/nuclease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:62,926,221...62,985,843
Ensembl chr 9:62,926,674...62,985,842 		JBrowse link
G PCNA proliferating cell nuclear antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991 		JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:531,905...567,430
Ensembl chr 2:531,085...566,840 		JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO5 F-box protein 5 involved_in ISO (PMID:17875940) UniProt PMID:17875940 NCBI chr13:80,453,345...80,467,590
Ensembl chr13:80,453,355...80,466,778 		JBrowse link
negative regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYNLL1 dynein light chain LC8-type 1 involved_in ISO (PMID:30464262), (PMID:37696958) UniProt PMID:30464262 PMID:37696958 NCBI chr11:115,851,020...115,855,526
Ensembl chr11:115,851,381...115,851,647 		JBrowse link
negative regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:19906994) ComplexPortal PMID:19906994 NCBI chr 5:74,190,409...74,196,589
Ensembl chr 5:74,190,947...74,195,972 		JBrowse link
G GMNN geminin DNA replication inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:47,462,647...47,474,445
Ensembl chr17:47,461,645...47,474,417 		JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG7 autophagy related 7 ISO RGD PMID:23800874 RGD:11557986 NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070 		JBrowse link
G LIG3 DNA ligase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:28,487,953...28,511,945
Ensembl chr16:28,490,434...28,511,130 		JBrowse link
nuclear DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:25,536,911...25,597,911
Ensembl chr16:25,538,131...25,597,695 		JBrowse link
G DONSON DNA replication fork stabilization factor DONSON involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:58,598,341...58,627,279
Ensembl chr 2:58,598,967...58,609,316 		JBrowse link
G RPA4 replication protein A4 NOT|involved_in ISO (PMID:19116208), (PMID:19942684) UniProt PMID:19116208 PMID:19942684 NCBI chr  X:85,323,910...85,325,997 JBrowse link
G ZNF830 zinc finger protein 830 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21191184) TreeGrafter
MGI		 PMID:21191184 GO_REF:0000118 NCBI chr16:28,468,548...28,470,150
Ensembl chr16:28,468,616...28,469,734 		JBrowse link
Okazaki fragment processing involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIG1 DNA ligase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:41,354,701...41,405,417
Ensembl chr 6:41,351,389...41,403,421 		JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2F7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266) UniProt PMID:23064266 MGI:5449497 NCBI chr11:72,598,220...72,642,366
Ensembl chr11:72,599,353...72,641,420 		JBrowse link
G E2F8 E2F transcription factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:45,751,937...45,772,698
Ensembl chr 1:45,756,301...45,772,632 		JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPM1 nucleophosmin 1 ISO RGD PMID:8123045 RGD:11535022 NCBI chr23:73,555,020...73,575,910
Ensembl chr23:73,555,260...73,575,925 		JBrowse link
positive regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146) CAFA PMID:11125146 NCBI chr 5:74,190,409...74,196,589
Ensembl chr 5:74,190,947...74,195,972 		JBrowse link
positive regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK2 cyclin dependent kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20215406) Ensembl
MGI		 PMID:20215406 GO_REF:0000107 NCBI chr11:51,905,085...51,910,209
Ensembl chr11:51,905,115...51,909,907 		JBrowse link
G CIZ1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO (PMID:20215406)
(PMID:15585571)		 MGI PMID:15585571 PMID:20215406 NCBI chr12:9,939,984...9,961,913
Ensembl chr12:9,940,696...9,962,235 		JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENDOG endonuclease G involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:9,322,828...9,326,833
Ensembl chr12:9,322,892...9,326,549 		JBrowse link
G MTNAP1 mitochondrial nucleoid associated protein 1 involved_in ISO (MGI:7564184|PMID:37676315) UniProt PMID:37676315 MGI:7564184 NCBI chr16:48,388,665...48,404,425
Ensembl chr16:48,386,342...48,403,958 		JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:110,492,340...110,504,176
Ensembl chr21:110,492,377...110,504,177 		JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR1 fibroblast growth factor receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2161540) Ensembl
MGI		 PMID:2161540 GO_REF:0000107 NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508 		JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler involved_in ISO (MGI:5568153|PMID:24651726) UniProt PMID:24651726 MGI:5568153 NCBI chr  X:66,449,830...66,737,220
Ensembl chr  X:66,448,449...66,737,164 		JBrowse link
G CDC7 cell division cycle 7 involved_in ISO (PMID:15668232) UniProt PMID:15668232 NCBI chr20:41,714,250...41,739,159
Ensembl chr20:41,715,572...41,739,138 		JBrowse link
G DBF4 DBF4-CDC7 kinase regulatory subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:61,029,913...61,062,806
Ensembl chr21:61,029,498...61,062,433 		JBrowse link
G INO80 INO80 complex ATPase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:41,878,648...42,017,526
Ensembl chr26:41,898,723...42,017,736 		JBrowse link
G LOC103243316 protein DBF4 homolog B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:61,652,845...61,693,154 JBrowse link
G WIZ WIZ zinc finger involved_in ISO (PMID:23545495) UniProt PMID:23545495 NCBI chr 6:14,025,533...14,052,834 JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SENP2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (PMID:19090619) MGI PMID:19090619 NCBI chr15:3,805,916...3,853,529 JBrowse link
regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZNF365 zinc finger protein 365 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:68,872,683...68,900,911
Ensembl chr 9:68,871,827...68,900,724 		JBrowse link
regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase involved_in ISO (PMID:25901030) UniProt PMID:25901030 NCBI chr29:9,046,485...9,152,320
Ensembl chr29:9,045,373...9,152,254 		JBrowse link
regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 5:74,190,409...74,196,589
Ensembl chr 5:74,190,947...74,195,972 		JBrowse link
G GMNN geminin DNA replication inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:47,462,647...47,474,445
Ensembl chr17:47,461,645...47,474,417 		JBrowse link
G KAT7 lysine acetyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:43,508,888...43,548,411
Ensembl chr16:43,510,483...43,548,517 		JBrowse link
G MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein involved_in ISO (PMID:24064211) ComplexPortal PMID:24064211 NCBI chr 4:51,454,155...51,464,823
Ensembl chr 4:51,455,506...51,462,302 		JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr29:8,117,198...8,171,956 JBrowse link
G WRNIP1 WRN helicase interacting protein 1 involved_in ISO (PMID:15670210) UniProt PMID:15670210 NCBI chr17:69,366,565...69,386,950
Ensembl chr17:69,366,389...69,386,932 		JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine involved_in ISO (PMID:32183942) UniProt PMID:32183942 NCBI chr18:61,767,806...61,834,994
Ensembl chr18:61,799,324...61,834,973 		JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15980864) Ensembl
MGI		 PMID:15980864 GO_REF:0000107 NCBI chr20:92,605,495...92,648,110
Ensembl chr20:92,605,309...92,648,114 		JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:8,426,920...8,438,331
Ensembl chr11:8,428,922...8,431,641 		JBrowse link
G CDT1 chromatin licensing and DNA replication factor 1 acts_upstream_of_or_within ISO (PMID:11850834) MGI PMID:11850834 NCBI chr 5:74,190,409...74,196,589
Ensembl chr 5:74,190,947...74,195,972 		JBrowse link
G DACH1 dachshund family transcription factor 1 involved_in ISO (MGI:5619482|PMID:16980615) CACAO PMID:16980615 MGI:5619482 NCBI chr 3:50,591,136...51,020,042 JBrowse link
G ILKAP ILK associated serine/threonine phosphatase ISO RGD PMID:9857069 RGD:632254 NCBI chr10:124,191,926...124,225,735
Ensembl chr10:124,190,785...124,225,678 		JBrowse link
G NUGGC nuclear GTPase, germinal center associated involved_in ISO (PMID:19734146) UniProt PMID:19734146 NCBI chr 8:26,129,593...26,190,881 JBrowse link
replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLFN11 schlafen family member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:28,819,647...28,842,121
Ensembl chr16:28,817,666...28,842,065 		JBrowse link
G TIMELESS timeless circadian regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:52,371,781...52,408,923
Ensembl chr11:52,372,375...52,389,284 		JBrowse link
G TIPIN TIMELESS interacting protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr26:17,194,859...17,214,671
Ensembl chr26:17,198,734...17,214,810 		JBrowse link
replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASF1A anti-silencing function 1A histone chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:54,972,514...54,988,436
Ensembl chr13:54,969,299...54,988,558 		JBrowse link
G ATR ATR serine/threonine kinase involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr15:48,048,785...48,173,120
Ensembl chr15:48,048,882...48,173,137 		JBrowse link
G ATRX ATRX chromatin remodeler involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:66,449,830...66,737,220
Ensembl chr  X:66,448,449...66,737,164 		JBrowse link
G BLM BLM RecQ like helicase involved_in ISO (PMID:17115688)
(MGI:6467697|PMID:29125140)		 UniProt PMID:17115688 PMID:29125140 MGI:6467697 NCBI chr29:9,046,485...9,152,320
Ensembl chr29:9,045,373...9,152,254 		JBrowse link
G BOD1 biorientation of chromosomes in cell division 1 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr23:75,760,925...75,770,919 JBrowse link
G BOD1L1 biorientation of chromosomes in cell division 1 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:36,560,501...36,619,215
Ensembl chr27:36,560,749...36,620,191 		JBrowse link
G BRCA2 BRCA2 DNA repair associated acts_upstream_of_or_within ISO (PMID:14681210) MGI PMID:14681210 NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213 		JBrowse link
G CDK9 cyclin dependent kinase 9 involved_in ISO (PMID:20930849) UniProt PMID:20930849 NCBI chr12:10,342,240...10,346,792
Ensembl chr12:10,342,801...10,346,502 		JBrowse link
G CENPS centromere protein S involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:121,333,554...121,343,893
Ensembl chr20:121,340,995...121,353,902
Ensembl chr20:121,340,995...121,353,902 		JBrowse link
G CENPX centromere protein X involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:73,905,670...73,910,622
Ensembl chr16:73,905,600...73,910,322 		JBrowse link
G DDX11 DEAD/H-box helicase 11 involved_in ISO (PMID:26503245) UniProt PMID:26503245 NCBI chr11:9,260,206...9,290,308
Ensembl chr11:9,260,239...9,291,162 		JBrowse link
G DONSON DNA replication fork stabilization factor DONSON involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:58,598,341...58,627,279
Ensembl chr 2:58,598,967...58,609,316 		JBrowse link
G EME1 essential meiotic structure-specific endonuclease 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:42,949,059...42,957,323
Ensembl chr16:42,949,570...42,955,312 		JBrowse link
G EME2 essential meiotic structure-specific endonuclease subunit 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:1,682,232...1,685,863
Ensembl chr 5:1,682,249...1,685,260 		JBrowse link
G ETAA1 ETAA1 activator of ATR kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:39,658,974...39,673,093
Ensembl chr14:39,659,873...39,673,259 		JBrowse link
G EXD2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:31255466) UniProt PMID:31255466 NCBI chr24:46,431,309...46,480,500
Ensembl chr24:46,444,282...46,482,845 		JBrowse link
G FAM111A FAM111 trypsin like peptidase A involved_in ISO (PMID:32165630) UniProt PMID:32165630 NCBI chr 1:14,405,991...14,412,170 JBrowse link
G FANCM FA complementation group M involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:22,255,750...22,327,191
Ensembl chr24:22,256,236...22,329,609 		JBrowse link
G FBH1 F-box DNA helicase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:6,001,071...6,047,512
Ensembl chr 9:6,013,908...6,047,753 		JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:89,886,102...89,917,485
Ensembl chr14:89,888,853...89,911,293 		JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr17:1,781,156...1,783,344
Ensembl chr17:1,781,026...1,783,111 		JBrowse link
G MMS22L MMS22 like, DNA repair protein involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr13:76,611,574...76,750,893
Ensembl chr13:76,611,517...76,750,616 		JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit involved_in ISO (PMID:17289582), (PMID:18413719) ComplexPortal PMID:17289582 PMID:18413719 NCBI chr 1:8,410,571...8,411,793 JBrowse link
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:23,597,210...23,634,262
Ensembl chr25:23,597,464...23,629,169 		JBrowse link
G OOEP oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr17:1,775,192...1,777,214
Ensembl chr17:1,775,955...1,776,982 		JBrowse link
G PCNA proliferating cell nuclear antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991 		JBrowse link
G POLQ DNA polymerase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:59,336,506...59,448,609
Ensembl chr22:59,336,842...59,448,604 		JBrowse link
G PRIMPOL primase and DNA directed polymerase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:130,611,105...130,653,614
Ensembl chr 7:130,611,133...130,657,450 		JBrowse link
G RAD51 RAD51 recombinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22778135) Ensembl
MGI		 PMID:22778135 GO_REF:0000107 NCBI chr26:42,281,085...42,319,394
Ensembl chr26:42,279,608...42,318,169 		JBrowse link
G RECQL RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:21,334,601...21,366,943
Ensembl chr11:21,331,584...21,366,979 		JBrowse link
G RFWD3 ring finger and WD repeat domain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:53,045,408...53,092,214
Ensembl chr 5:53,045,465...53,092,494 		JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:531,905...567,430
Ensembl chr 2:531,085...566,840 		JBrowse link
G SETMAR SET domain and mariner transposase fusion gene involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:40,389,390...40,403,917
Ensembl chr22:40,389,485...40,403,898 		JBrowse link
G SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:102,253,187...102,319,356
Ensembl chr10:102,255,453...102,319,330 		JBrowse link
G TIPIN TIMELESS interacting protein involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr26:17,194,859...17,214,671
Ensembl chr26:17,198,734...17,214,810 		JBrowse link
G TONSL tonsoku like, DNA repair protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:138,641,514...138,657,429
Ensembl chr 8:138,641,575...138,656,673 		JBrowse link
G TRAIP TRAF interacting protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:11,220,152...11,262,942
Ensembl chr22:11,233,996...11,262,830 		JBrowse link
G WRN WRN RecQ like helicase involved_in ISO (PMID:17115688)
(PMID:12882351)		 UniProt PMID:12882351 PMID:17115688 NCBI chr 8:29,150,256...29,288,830
Ensembl chr 8:29,174,229...29,289,129 		JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:19,428,139...19,739,886
Ensembl chr10:19,427,652...19,572,384 		JBrowse link
replication fork reversal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARM1 coactivator associated arginine methyltransferase 1 involved_in ISO (PMID:33412112) UniProt PMID:33412112 NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:33412112) UniProt PMID:33412112 NCBI chr25:3,350,798...3,405,040 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr25:3,350,821...3,388,826 JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 involved_in ISO (PMID:22704558) UniProt PMID:22704558 NCBI chr10:19,428,139...19,739,886
Ensembl chr10:19,427,652...19,572,384 		JBrowse link
telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UPF1 UPF1 RNA helicase and ATPase involved_in ISO (PMID:21829167) BHF-UCL PMID:21829167 NCBI chr 6:17,291,189...17,328,768
Ensembl chr 6:17,291,175...17,330,193 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16919
    metabolic process 10498
      primary metabolic process 9190
        nucleobase-containing compound metabolic process 5214
          nucleic acid metabolic process 4702
            DNA metabolic process 916
              DNA replication 264
                DNA-templated DNA replication 158
                  DNA replication initiation + 33
                  DNA replication termination + 1
                  DNA replication, synthesis of primer 7
                  DNA strand elongation involved in DNA replication + 13
                  DNA unwinding involved in DNA replication + 20
                  DNA-dependent DNA replication DNA ligation + 0
                  DNA-templated DNA replication maintenance of fidelity + 56
                  cell cycle DNA replication + 41
                  mitochondrial DNA replication + 20
                  negative regulation of DNA-templated DNA replication + 9
                  plastid DNA replication 0
                  positive regulation of DNA-templated DNA replication + 15
                  pre-replicative complex assembly + 0
                  regulation of DNA-templated DNA replication + 36
                  replication of extrachromosomal circular DNA 0
                  rolling circle DNA replication 0
                  theta DNA replication 0
Path 2
Term Annotations click to browse term
  biological_process 16919
    metabolic process 10498
      organic substance metabolic process 10049
        organic cyclic compound metabolic process 5668
          nucleobase-containing compound metabolic process 5214
            nucleic acid metabolic process 4702
              DNA metabolic process 916
                DNA replication 264
                  DNA-templated DNA replication 158
                    DNA replication initiation + 33
                    DNA replication termination + 1
                    DNA replication, synthesis of primer 7
                    DNA strand elongation involved in DNA replication + 13
                    DNA unwinding involved in DNA replication + 20
                    DNA-dependent DNA replication DNA ligation + 0
                    DNA-templated DNA replication maintenance of fidelity + 56
                    cell cycle DNA replication + 41
                    mitochondrial DNA replication + 20
                    negative regulation of DNA-templated DNA replication + 9
                    plastid DNA replication 0
                    positive regulation of DNA-templated DNA replication + 15
                    pre-replicative complex assembly + 0
                    regulation of DNA-templated DNA replication + 36
                    replication of extrachromosomal circular DNA 0
                    rolling circle DNA replication 0
                    theta DNA replication 0
paths to the root